- The protocol in-vitro study only (identification, isolation and purification of active compounds. Also, gene expression analysis in Date palm cells. - Date palm is not medicinal plant. While the protocol needs to some corrections: 1-Study type: Need to correct. 2-Duration of study: need to define 30 day or month. 3-Supmission Type: Written Re-Submission ??? 4-What is the time period covered by the search: Written 2: What month or year ??? 5-Name of funding agent: Written abbreviation ASRT: Need full name. 6-Fund amount: Written 20.000: Need to write Type of the currency. 7-List of References: Need to corrections. 8- Gantt Chart and Flowcharts: Attach Full Thesis protocol. 9-Materials and Methods: Did not mentioned. 10-The site and date of collection of plants: Written January 2024: Need to correct.