National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Antioxidant and anti-inflammatory activity of flavonoids rich fraction from Dodonaea viscosa leaves with computer-guided docking study.

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

 تعديل العنوان العربى الى النشاط المضاد للأكسدة والمضاد للالتهابات للمكون الغني بالفلافونويدات من أوراق نبات الدودونيا (دودونيا فسكوسا) مع دراسة الإرساء الموجهة بالكمبيوتر

- Name of the institute and department is written in numbers.

- Submission Type: written Re-submission.

- Written not reviewed by scientific reviewing committee.

- Fund amount: Written number without writing the type of currency.

- Keywords: Need to add in-vitro.

- Secondary objectives: The first line is required to correct violet flowers to Dodonia leaves.

- Procedure in Details: It does not contain any references. It only contains the evaluation methods.

- Gantt and Flowcharts: Repeating the same words that were mentioned previously in Procedure in Details.

- Correct a word of invitro to be in-vitro (under title of Acute toxicity).

- Delete the under title of Side effects.

-The taxonomical identification of plants by specialized Taxonomist: The classification is written without mentioning the name of the person or institution that made the classification.

- Answer a question of the safety procedures taken to protect or mitigate the side effects: written there is no side effect of herbal extract, fractions or compounds. How and written in the Background, Spasmolytic activity could arise from the presence of quercetin and rutin in the seeds, bark, inflorescences and leaves (Al-Snafi, 2017).

- Answer a question of Purpose of the Waiver Request and your reasons for a waiver to consent. Written a lot of words that are repeated and incomprehensible. While the answer is that the study is in-vitro.

- There is no indication of Safety. Although in this study we are dealing with a plant that has Spasmolytic activity. And working in the laboratory with different equipment and chemicals.

- Flow-chart file: Duplicate twice.

- Payment-Document: Written the research does not require a Payment Document, as the study focuses on in vitro antioxidant and anti-inflammatory properties, and no animals will be involved. Correction required, all Research Team from National Research Centre.

- Signing date of the Commitment not written.

- Form 90 is not present.

 

Comment to the Committee

 نموذج 90 غير موجود ، الا انه موجود استمارة بعنوان تقييم بحث علميا تمهيدا لتقديمه الى لحنة أخلاقيات البحوث الطبية ، وموقعة من رئيس القسم أو القاءم بالفحص (د. معنزة عمران - رئيس القسم ووكيل المعهد)

  أخر المقترح البحثى فى فقرة التعليقات: مكتوب رجاء تحميل نموذج 90 من على الموقع  بكافة التوقيعات ورفعه على الموقع فى خلال 24 ساعة حتى لا يتم التاجيل ووضع اسم المعهد والقسم بدلا من الارقام. الا ان الباحث لم يستجيب لهذه الملاحضات

Informed consent form:

Waiver

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