- Principal Investigator Data: Scientific Degree: Written Ph.D. Correct to M.Sc.

- Name of the Institute and the Department Did not write.

- Role/tasks of the PI: written the Primary Objective of the study.

- Study Type: Written other without writing anything. Can be written Interventional study.

- Duration of the study: Written 1.5 years. While it is written in Gantt-chart 23 months (2 years).

- Procedure in Details: How to produce the enzyme is not written.

- In Procedure: did not write how the products are made nor did he specify the exact products.

- In Procedure: How to carry out the various estimates has not been written.

- Sample size and groups: Nothing is written in it, only written 1 ml sample size for each test groups include one blank and three trials.

- Gantt Chart: Its design is not correct, written 12 months in one place and written 23 months in another.

- In response to the question (Does this protocol involve the use of substances that may pose any health risk): The answer was No. How, the protocol involves microbiological work and usage different chemicals in laboratory work.

- List of References: there are 69 references, although there are only 17 references present only in the Background. It is required to delete the extra references.

- Application for Studies Involving Humans: The proposal includes conducting panel test for testing the sensory properties of the products. Despite that, did not mention the test details, the number of participants, the types of tests, or how they were conducted.

- In response to many questions about the participants, there is no answer. Everything is written in it (It is a panel test for testing the sensory properties of the products).

- Consent Form: The Form containing only the proposal title and the researcher's name, without any data and not signatures. The Consent Form should be written in accordance with the nature of the study.

- Commitment Form: Is not dated.

- Conflict of interest Form: Is not dated.