MREC Reviewer Comment
Protocol Title
Effects of Saffron on Docetaxel–Induced Liver Toxicity in Rats
Completely satisfied and informative data
Needs Explanation
Comments to the applicant
NA
Comment to the Committee
Required Action/Clarification
1- Experimental Design Harmonize the DTX dosage across all treated groups (8 mg/kg vs 10 mg/kg).
2-Euthanasia: Specify the anesthetic agent and the final method of sacrifice.
3- Cell Work: Confirm if the MDA-MB-231 work involves animal models (xenografts) or is strictly in vitro.
Informed consent form:
N/A
