MREC Reviewer Comment
Protocol Title
The Role of Janus Kinase inhibitors in Ameliorating Nephropathy and Neuropathy in Diabetic-induced Rats
Completely satisfied and informative data
Needs Explanation
Comments to the applicant
Non
Comment to the Committee
- How the sample size of six rats per group was determined. A power analysis should be included to justify the chosen sample size.
The summary mentions wanting to elucidate the molecular pathways, but details on specific mechanistic investigations are not provided. Consider including planned methods for exploring these pathways (e.g., Western blotting, qRT-PCR).
Informed consent form:
N/A
