1- What is the funding amount?

2- Why are the procedures written in the past tense?

3- Ciprofloxacin induces depressive like behavior and not depression

4- Why sacrifice the animals? retro-orbital samples of 3 ml do not necessitate sacrificing the animals.

5- How was the sample size calculated? The reference should only be a guide

6- What is the social relevance of the study?

7- Justify why there is no need for a pilot study?

8- Explain why and how 3 Rs did not determine any possible reduction?

9- Pain and stress: retroorbital samples are painful?