The discovery of a new drug mentioned in the secondary objective is actually a primary objective. The author needs to state the specific or secondary objective in a clear form.

Please, upload a flow chart that demonstrates the procedures done for each group of rats.

The protocol was not reviewed by scientific reviewing committee.

Back ground : many paragraphs written without references  and at the end the text is cut off

 Procedure in details is very brief and without details . In addition to writing  histopathological   examination not histology  examination.

Treatment by force feeding the extract daily is written in Gantti chart for one month but in flow chart is written 2 weeks which is right.

In severity of pain in animal s written as no pain although the following question mention and describe the anticipated pain Frequency: The pain of the syringe during injection is used to prepare the model, treatment is administered orally, and cervical dislocation is at the end of the experiment.