National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Formulation of co-enzyme Q10 loaded nanovesicles for oral use for improvement of its biodistribution

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

Correction of English title

Formulation of Co-Enzyme Q10 Loaded Nanovesicles for Oral Use to improve its bioavailability in rats

تعديل العنوان العربى

تركيبة حويصلات نانوية محملة بالإنزيم المساعد Q10 للاستخدام الفموى لتحسين توزيعه الحيوي فى الجرذان

 
Anticipated Start Date (2026-04-01) please write (The work will start after completion of all necessary approvals)
 
Fund Amount: self (please write the estimated cost of the work)

Study Power (mention the equation of study power)

No reference for the dose of co-enzyme Q10 (Dosage: 10 mg???)

 

Confirmation of death in animals: (animals will be sacrificed to extract their organist) it is wrong answer please write the essential indicators include fixed/dilated pupils, no heart beat and respiration

Comment to the Committee

Correction of English title

Formulation of Co-Enzyme Q10 Loaded Nanovesicles for Oral Use to improve its bioavailability in rats

تعديل العنوان العربى

تركيبة حويصلات نانوية محملة بالإنزيم المساعد Q10 للاستخدام الفموى لتحسين توزيعه الحيوي فى الجرذان

 
Anticipated Start Date (2026-04-01) please write (The work will start after completion of all necessary approvals)
 
Fund Amount: self (please write the estimated cost of the work)

Study Power (mention the equation of study power)

No reference for the dose of co-enzyme Q10 (Dosage: 10 mg???)

 

Confirmation of death in animals: (animals will be sacrificed to extract their organist) it is wrong answer please write the essential indicators include fixed/dilated pupils, no heart beat and respiration

Informed consent form:

N/A

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