National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Nebulized TNF-α-Preconditioned Mesenchymal Stem Cell-Derived Exosomes for Alveolar Regeneration and Inflammation Modulation in a Chronic Cigarette Smoke-Induced Rat Model of COPD

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

Write the Institute and Department for you

Where the names and affiliations of team works

The Protocol Was not Reviewed By Scientific Reviewing Committee

Fund Amount: write the value of the fund

Sample Size calculation? She did not write the reference

Write from where you got the ( Human cell lines (BEAS-2B), mesenchymal stem cell-derived exosomes)

Write the dose of each drugs you will use and the references of them

The methodology needs more details

There are no references in the bake ground, methodology or sample size although he writes a list of references

Category is not research (it is project)

Department and institutional approval: نموذج 90 غير ممضى من رئيس القسم  و عميد النعهد

 لا يوجد نموذج التعهد بالدفع عند الموافقة على المشروع لانة مشروع مشترك مع جهة امنية ICGEB

Comment to the Committee

Write the Institute and Department for you

Where the names and affiliations of team works

The Protocol Was not Reviewed By Scientific Reviewing Committee

Fund Amount: write the value of the fund

Sample Size calculation? She did not write the reference

Write from where you got the ( Human cell lines (BEAS-2B), mesenchymal stem cell-derived exosomes)

Write the dose of each drugs you will use and the references of them

The methodology needs more details

There are no references in the bake ground, methodology or sample size although he writes a list of references

Category is not research (it is project)

Department and institutional approval: نموذج 90 غير ممضى من رئيس القسم  و عميد النعهد

 لا يوجد نموذج التعهد بالدفع عند الموافقة على المشروع لانة مشروع مشترك مع جهة امنية ICGEB

Informed consent form:

N/A

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