National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

TiO₂NP-loaded doxorubicin mitigates oxidative stress, neuroinflammation, and apoptosis in DMBA induced brain damage

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

تعديل العنوان الانجليزى ليناسب العربى فى كلمة تأثير

 She did not write the fund amount

She mention that the duration of study is one month although in methodology she will give the rat DMBA drug and booster dose after 6 weeks then inject with doxorubicin for one month

Gant chart: needs modification according to procedure

Justification Of Animal Number she mention 480 ???

 Correct the Animal Disposition : Dead animals will be collected in red plastic bags, and then we will give them to the animal house in NRC to get rid of by burning.

 

 

Comment to the Committee

تعديل العنوان الانجليزى ليناسب العربى فى كلمة تأثير

 She did not write the fund amount

She mention that the duration of study is one month although in methodology she will give the rat DMBA drug and booster dose after 6 weeks then inject with doxorubicin for one month

Gant chart: needs modification according to procedure

Justification Of Animal Number she mention 480 ???

 Correct the Animal Disposition : Dead animals will be collected in red plastic bags, and then we will give them to the animal house in NRC to get rid of by burning.

 

 

Informed consent form:

N/A

Medicinal Update Comments for Researcher

Mie Mohammed

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