•                The protocol is well  written and contains all information related to the study 

•        Write the name of the institute and department  in the Principal Investigator Data of PI        

•        The protocol is reviewed by scientific reviewing committee .therefore write yes

not no

•        Fund amount is determined approximately

•        The  numbers of Co-Investigators  are 4 not 2

مكتوب فى اقرار الباحثين  ان الفريق البحثى المساد 4 وهم د. سماح ود.  ريم ود .شريف ود. فاطمة الزهراء ولكن فى البروتوكول مكتوبد. ريم و د. شريف فقط وهم من خارج المركز

برجاء التوضيح

•        The background is not  supported by any references

•        In Procedure in details :  needs more details about total  number of animals and number in each group, age ,sex .weight of experimental animals as mention in sample size and groups.         Mention the references for methods which used

•        There are list of references but there is no references in the protocol