National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Therapeutic Potential of Calotropis procera (Aiton) Seed Fixed Oil in Wound Healing: Cellular and Animal Model Insights"

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

•        Write the name of the institute and department  in the Principal Investigator Data of PI        

•        The protocol is not reviewed by scientific reviewing committee

•         

•        Select Date: 2026-07-20 no detect the start date of work  but  write the work start after completion   of all necessary approvals

•        Fund amount is determined approximately

•        Please write the primary  objective clearly  not as methodology .write different parts of plant  instead of  different oranges of plant .

•        The background is not  supported by any references

•         Please review the total numbers of animals in the  protocol ; in experimental animals, spherical wound  operation , experimental design  , sample size ,…

•        Mention the references for methods which used in the protocol

•         

•        Why is the  Gantt  chart written in terms of % of time ? explain

•        Please write the name of the drug and Route of  injection  Euthanasia part of the study design

Write ethically  details in If more than one method is used per species please list all methods and Confirmation of Death ,  Animals Animal disposition and in What will be the method of disposal of dead animals

Comment to the Committee

•        Write the name of the institute and department  in the Principal Investigator Data of PI        

•        The protocol is not reviewed by scientific reviewing committee

•         

•        Select Date: 2026-07-20 no detect the start date of work  but  write the work start after completion   of all necessary approvals

•        Fund amount is determined approximately

•        Please write the primary  objective clearly  not as methodology .write different parts of plant  instead of  different oranges of plant .

•        The background is not  supported by any references

•         Please review the total numbers of animals in the  protocol ; in experimental animals, spherical wound  operation , experimental design  , sample size ,…

•        Mention the references for methods which used in the protocol

•         

•        Why is the  Gantt  chart written in terms of % of time ? explain

•        Please write the name of the drug and Route of  injection  Euthanasia part of the study design

Write ethically  details in If more than one method is used per species please list all methods and Confirmation of Death ,  Animals Animal disposition and in What will be the method of disposal of dead animals

Informed consent form:

N/A

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