National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Assessment of Biological and Chemical Influence of the Natural plant Garlic on Lipid Metabolism and the Cardiovascular risk as an Environmental Plant Medicine

Completely satisfied and informative data

Disapprove

Comments to the applicant

1) In the experimental procedure  each participant will take 5 gm of raw garlic daily for 4 weeks ,which is a toxic dose ,that can cause  severe toxicity and side effects to the participants as damage  of the blood corpuscles ,bleeding risk ,hemolytic anemia ,stomach inflammation ,gastritis ,allergic reactions ,conjuctivitis ,headache ,dizziness...ect. ,while referring to the Pharmacopoea ,Egyptian Drug Authority and references ,the safe and effective dose of raw or powdered garlic which is used for treatment of Dyslipidemia and reduction of cardiovascular risk is(400-1200 mg) .(Please see reference) . 2)The  template lacks the members of the Team Work,most of the required data and the scientific professional style . Reference :Egyptian Drug Authority ,Egyptian Herbal Monograph ,Medicinal Plants used in Egypt (Vol.3)(2024) , Allium sativum  L..

Comment to the Committee

Reference :Egyptian Drug Authority ,Egyptian Herbal Monograph ,Medicinal Plants used in Egypt (Vol.3)(2024) , Allium sativum L..

Informed consent form:

N/A

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