MREC Reviewer Comment
Protocol Title
Protective Effects of Benzoic and Salicylic Acids Against Ochratoxin A (OTA)-Induced Toxicity and Ochratoxicosis Symptoms in Female Mice
Completely satisfied and informative data
Needs Explanation
Comments to the applicant
1. Revise english and Arabic titles.
2. Explain why use Female mice
3. Explain the source of ochratoxin A.
4. Clarify the type of biochemical tests used for detection of liver and kidney functions
5- OTA was administered orally at a dose of 2 ml per mouse daily for four weeks. (How will the Benzoic and salicylic acids be administered?)
6. Can use the salts of acids like sodium as more safe than pure acids
Comment to the Committee
1- English title: against
2- Arabic Title لحمضي - الأوكراتوكسين أ
3- Method of preparation of the Ocratxin A
4- Types of Biochemical tests
5. The number of mice in each group (3) is too few for the experiment.
Informed consent form:
N/A
