-Add fund amount.
The first main group (healthy animals)
-Subgroup 3: It is mentioned that ten rats will be administered peanut protein (hydrolyzed fraction), what is its source?
The second main group (diseased animals)
- It is mentioned that the second main group will be diseased animals (40 rats) that were orally administered Corvast, add that this is simvastatin market product, and add company name.
- It is mentioned that Subgroup 2: ten rats will be administered isolated protein (1 g/kg/day for 15 days orally) and will be kept in a peanut isolated protein-treated group. Subgroup 3: ten rats will be administered the hydrolyzed protein (1 g/kg/day for 15 days orally) and will be kept in a peanut hydrolyzed-treated group, clarify what will be administered by these subgroups.
-The group administering Flax isolated protein is not mentioned.
* What are the parameters which will be measured in blood samples?
* In the Gantt chart, it is mentioned that treatment by force-feeding the protein daily at a dose of 1000 mg/kg, clarify how force-feeding will be done, and add what will be administered to induce muscle atrophy.
And it is mentioned that treatment by force-feeding the extract daily at a dose of 500 mg/kg, which extract? also this dose is not mentioned anywhere in the proposal
*In the flow chart, it is mentioned that Induction of muscular atrophy by administration 80 mg/kg body weight orally for tow weekly, clarify what will be administered and correct spelling mistakes.
- it is mentioned that: We performed a pilot study to discover the statin-muscular atrophy model because this is the first experience in this model, while this model is presented in literature.
- In animal disposition item, add the answer
- The protocol is full of spelling mistakes, please correct.
نموذج 90 غير موضح به إذا كان البروتولول سليم علميا و تمت الموافقة عليه أم لا كما أن إصدار النموذج قديم