National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Clinical Impact of Diode Laser on Trueness, Precision, and Quality of Life of Complete Denture Wearers (Clinical Study)

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

The study's objective is to assess the precision of maxillary dentures following exposure to various disinfection mechanisms. However, the efficacy of diode lasers as disinfectants was not validated.

Either include supplementary testing in the study design to demonstrate its anti-fungal or anti-bacterial properties, or provide references from previous studies that support its disinfectant properties.

The informed consent needs thorough revision, and any unnecessary data that is unrelated to the study should be omitted.

Comment to the Committee

Informed consent form:

Needs Modification

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