National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Bioactive Carboxymethyl Cellulose/Dextran /Diatomite scaffolds: Antimicrobial Activity and Bone Regeneration.

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

Kindly rewrite the procedures in the present tense.

Please indicate the source of the bacterial strains and where they are purchased from.

Also, where are the MG-63 cell lines purchased from and provide the suitable referencing information of the cell line?

As for the bone marrow stromal cells, are these primary isolated cells? If not, kindly mention the source and suitable referencing information.

Gant and flow charts are missing.

The consent form provided under the title "ccompleted consent form" is the wrong document. Kindly check.

Also, under "other forms, " the document titled CONSENT is not suitable. The PI should justify first the source of both cell lines with proper referencing information, and then a waiver of informed consent could be considered.

Comment to the Committee

Informed consent form:

Needs Modification

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