National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Biosynthesis and characterization of Cu-Se bimetallic nanoparticles: effective approach as anticancer agent

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

The protocol is well written but needs some modifications:

Comment to the Committee

The protocol is well written but needs some modifications:

1- The protocol has not been reviewed by the Scientific Review Committee

2- In the Gantt chart part, the Flow chart was placed by mistake

3- The source of Ehrlich ascites carcinoma cells has not been clarified

4- In the experimental procedures section, only the name of the methods was mentioned without details

5- There is a question: Why was copper chosen in the manufacture of nanoparticles despite its known toxicity? Can it be replaced with another element, such as iron, which is known to have less toxicity?

Informed consent form:

N/A

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