National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

The biosynthesis of zinc oxide nanoparticles and chitosan/zinc oxide nanoconjugates of soil bacteria and exploration of their in vitro biological applications.

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

The protocol needs modifications

Comment to the Committee

The protocol needs modifications: 1- The data of the principal investigator and members of the research team are written in numerical form.

2- The protocol has not been reviewed by a scientific committee.

3- The source of the cancerous liver, colon and lung cells that will be used to perform the cytotoxicity test in the laboratory has not been clarified.

4- The experimental design that includes the concentration of nanoparticles in the treatment of cancer cells and different groups (treated and untreated cells) (treatment duration) has not been clarified.

5- The number of analyses is very large and requires a high amount of funding (although it is self-funded)

Informed consent form:

Needs Modification

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