National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

A direct comparison of initiated and conventional non-initiated diode-laser fiber tips in smear layer removal

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

The protocol is good but requires modifications.

Comment to the Committee

The protocol is good but requires modifications.

العنوان العربى: كتابة ليزر بدلا من ليز

Is there a difference between "comparison" and "direct comparison"? In other words, can "direct" be removed from the title?

2- Principal Investigator details (department and institute not listed)
3- Research funding details were not specified; "self-funding" was stated instead.

4- The scientific background is very brief and phrased as an objective rather than a review of studies relevant to the protocol.
5- In the practical section, the specific type of tooth—whether anterior or posterior—was not specified (does the effect vary depending on the tooth type?).

6- Sample size calculation: The reference used for this calculation was not cited.
7- As the study involves teeth *in vitro*, the principal investigator is requesting a waiver of informed consent; however, the researcher did not address questions related to this waiver, such as: the type of waiver requested, an explanation of why conducting the research is not practically feasible without the waiver or an approved modification, and the reasons for requesting the waiver.

Informed consent form:

Needs Modification

Login

Email Address *
Enter your username or email address
password *
Enter your password

Reset Password

Enter Your Email
Please insert your email and check your email for rest password link

Still not a member? Register