MREC Reviewer Comment
Protocol Title
Studying the possible protective role of the extract of aerial parts of Rudbickia hirta against colitis induced by acetic acid in rats
Completely satisfied and informative data
Needs Explanation
Comments to the applicant
NA
Comment to the Committee
The plant name is consistently misspelled as "Rudbickia hirta" throughout the protocol. The correct spelling is Rudbeckia hirta.
The Researcher needs to clarify the terminal procedure. The acceptable method is terminal anesthesia overdose (ketamine/xylazine) followed by an approved secondary physical method (e.g., cervical dislocation or exsanguination) to ensure death. All references to CO2 euthanasia at the time of colitis induction must be removed, as it is incorrect.
Informed consent form:
N/A
