National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

protective function of crude and nano Thyme-Eucalyptus oils admixture for ameliorative impact against aflatoxins (B1-G1)in rat tissues

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

1. There are no designated research teams. 

2. While they have obtained approval from their department and institute, they state that there is no scientific review committee in place. 

3. The funding amount is missing. 

4. The study involves a total of 100 rats, which is excessive. Each group will consist of 5 rats, and there are 6 groups in total. 

5. The authors mention the use of anesthesia at times but also state that there is none. 

6. A Gantt chart is a table that summarizes the results, indicating the work that has already been completed. 

7. Many references were not cited in either the background or the proposal. 

8. There are several repeated paragraphs throughout the document. 

9. The animals will be administered 0.5 mg AFB1/kg body weight for 5 weeks, which may cause pain, contrary to the authors' claims that the animals will not experience any pain. 

Comment to the Committee

Informed consent form:

N/A

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