National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Deciphering the Potential of Cymbopogon citratus as an Anti-Obesity Agent: Phytochemical Profiling, in Vivo Evaluations and Molecular Docking Studies

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

Protocol Title in Arabic: Need to correction

تصحيح معملية حيث ان الدراسة تتم على الفئران

تصحيح نظرية الى الالتحام الجزيئى

-Duration of the study: You mention 8 weeks. While in Gant Chart, the study will do in 9 periods take 16 months.

- Background is very verry little, need to complete.

-Flowcharts: You mention Gene expiration only, must you mention all steps.

-What is the expected severity of pain the animal will suffer in your study: You mention No pain, how. is Little  pain. 

-Describe the anticipated pain or distress for animals. You mention No pain, how. is little pain. 

-Agent / Substance: Other: Orlistat.  You mention Dosage: 125mg/kg/day, Correct to 10 mg.

-Animal Housing Requirements. You did not mention how the animals were housing and management. 

 

 

 

Comment to the Committee

- The protocol needs to review by scientific reviewing committee.

-Background need to Background. 

Informed consent form:

N/A

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