The protocol was not reviewed by scientific reviewing committee:

Fund amount: self (please write the amount)

I suggest the following paragraph for Hypothesis, Rationale and Scientific Validity

“The hypothesis that allantoin and glutathione vesicles protect against UV-induced photoaging in rats is scientifically valid, based on the established roles of glutathione as a master antioxidant, allantoin as a healing and anti-inflammatory agent, and vesicular carriers as efficient dermal delivery systems. Together, these components can synergistically reduce oxidative stress, prevent ECM degradation, and enhance skin repair, supporting their evaluation in animal photoaging models”

It is preferable for the background to include increasingly recent references.

It is better to revise and write the tasks in Gantt
It is better to include more recent references in your writing.