MREC Reviewer Comment
Protocol Title
Completely satisfied and informative data
Comments to the applicant
PI Name: Ahmed abdel fattah ibrahim Soliman
English Title: A comparative study and biological evaluation of new unsymmetrical carbamide derivatives bearing aliphatic amines: Practical synthesis, in vitro and molecular dynamic studies
Ø It would be better if molecular dynamic studies were corrected to in silico molecular docking studies.
Principal Investigator Data
Affiliation: NRC
Ø The affiliation for the PI should be completed.
1Co-Investigator
Affiliation: Organometallic and Organometalloid Chemistry
Ø The affiliation should be corrected.
Ø Materials and methods were written in the past, not in the future.
Ø The references written in the section on materials and methods should be written, and it is better if they are written as author and date, not numerically.
Ø The source of cell lines should be mentioned
Ø Generally, materials and methods look like copy-and-paste from a published paper without revision, as they include results, particularly the molecular docking part, as well as numerical references.
Ø The part of Molecular Docking Simulation Preparation of Protein Receptors was written in the past and included results such as Table 1, so I suggest the materials and methods should be rewritten again.
Comment to the Committee
PI Name: Ahmed abdel fattah ibrahim Soliman
English Title: A comparative study and biological evaluation of new unsymmetrical carbamide derivatives bearing aliphatic amines: Practical synthesis, in vitro and molecular dynamic studies
Ø It would be better if molecular dynamic studies were corrected to in silico molecular docking studies.
Principal Investigator Data
Affiliation: NRC
Ø The affiliation for the PI should be completed.
1Co-Investigator
Affiliation: Organometallic and Organometalloid Chemistry
Ø The affiliation should be corrected.
Ø Materials and methods were written in the past, not in the future.
Ø The references written in the section on materials and methods should be written, and it is better if they are written as author and date, not numerically.
Ø The source of cell lines should be mentioned
Ø Generally, materials and methods look like copy-and-paste from a published paper without revision, as they include results, particularly the molecular docking part, as well as numerical references.
Ø The part of Molecular Docking Simulation Preparation of Protein Receptors was written in the past and included results such as Table 1, so I suggest the materials and methods should be rewritten again.
