National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Zinc sulphate alleviates Olanzapine induced alteration in hepatic protein patterns and antioxidant defense system in rats

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

Duration of study is 8 weeks

The  protocol was reviewed by scientific committee (90)

Secondary Objectives is not publication

Hypothesis needs modification

Method of sample size calculation?

Mention safety precautions that will be followed during blood and tissue sampling

List Who Will Monitor Or Observe Animals

Indicate The Schedule Of Monitoring

Is Euthanasia Part Of The Study Design

Confirmation Of Death In Animals

Animal Housing Requirements

Animal Disposition

What Will Be The Method Of Disposal Of Dead Animals? by freezing the remains of dead animals in red bags to be delivered to health and safety unite 

Will Researchers Perform Technical Procedures On Animals In Addition To Routine Husbandry? who will do all the procedures of the study

 

Comment to the Committee

Informed consent form:

N/A

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