MREC Reviewer Comment
Protocol Title
Completely satisfied and informative data
Comments to the applicant
العنوان العربى و الانجليزى محتاج تعديل لانه كدة نتيجة و ليس بحث
Does Fasudil Mitigates Cisplatin-Induced Kidney Injury In Rats Through Regulating ERK1/2/Nrf2, NF‐ΚB/TNF‐Α, And Angiotensin-II/TGF-Β1 Signaling Pathway?
هل يخفف فاسوديل من إصابة الكلى الناجمة عن سيسبلاتين في الجرذان من خلال تنظيم مسار إشارات ERK1/2/Nrf2 و NF-ΚB/TNF-Α و Angiotensin-II/TGF-Β1؟
The Protocol Was Reviewed By Scientific Reviewing Committee: she said no although she attached form 90
Fund Amount: self (she must mention the proper cost)
She mention her affiliation as principle investigator as assistant researcher and in co-investigator as researcher
Hypothesis, Rationale and Scientific Validity: too short needs more details (Examination of renoprotective effects of fasudil)
Background: too short she did not mention any thing about the effect and uses of fasudil
She mention in the procedures (At the end of the study, 24 h urine and blood samples were collected.) how??????
Severity of Pain the Animal will suffer she mention minimal although there is I.P injection
Confirmation of Death in Animals she mention (Vital tissue dissection)
Animal Housing Requirements she mention (Specify the intended Animal Housing Facility)
Comment to the Committee
العنوان العربى و الانجليزى محتاج تعديل لانه كدة نتيجة و ليس بحث
Does Fasudil Mitigates Cisplatin-Induced Kidney Injury In Rats Through Regulating ERK1/2/Nrf2, NF‐ΚB/TNF‐Α, And Angiotensin-II/TGF-Β1 Signaling Pathway?
هل يخفف فاسوديل من إصابة الكلى الناجمة عن سيسبلاتين في الجرذان من خلال تنظيم مسار إشارات ERK1/2/Nrf2 و NF-ΚB/TNF-Α و Angiotensin-II/TGF-Β1؟
The Protocol Was Reviewed By Scientific Reviewing Committee: she said no although she attached form 90
Fund Amount: self (she must mention the proper cost)
She mention her affiliation as principle investigator as assistant researcher and in co-investigator as researcher
Hypothesis, Rationale and Scientific Validity: too short needs more details (Examination of renoprotective effects of fasudil)
Background: too short she did not mention any thing about the effect and uses of fasudil
She mention in the procedures (At the end of the study, 24 h urine and blood samples were collected.) how??????
Severity of Pain the Animal will suffer she mention minimal although there is I.P injection
Confirmation of Death in Animals she mention (Vital tissue dissection)
Animal Housing Requirements she mention (Specify the intended Animal Housing Facility)
