National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

In vitro and in vivo antidiabetic evaluation of newly synthesized coumarin and chromone derivatives

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

-          Role/Tasks in The Research/Project: Please put only your role in the study

-          Duration of the Study: Please correct the duration of study because you write 2 month and in Gantt chart 7 month

-          The Protocol Was Reviewed By Scientific Reviewing Committee: he write no although he attach the approval of department

-          Fund Amount: please put the amount of fund

-          How you are going to reduce or mitigate the risks: correct the answer it is not by burning the animal

-           He mention that he will do toxicity test on normal liver cell line but he did not mention any thing about this step and from where he got the cell line

-          A Describe How Pain or Distress Will Be Monitored,  B List Who Will Monitor or Observe Animals and  C Indicate the Schedule of Monitoring:  (A,B,C) They had the same answer that the rat becomes unconscious please  correct them

 لماذا لم يتم تقديم الحصول على موافقة لجنة الاخلاقيات من دكاترة المركز حيث انة مكتوب ان الجزء العملى سوف يتم بالمركز القومى للبحوث

-          What Will Be the Method of Disposal of Dead Animals? Correct the answer

نعم وذلك عن طريق المحرقة بالمركز القومى للبحوث  برجاء تصحيح الاجابة حيث لايوجد محرقة بالمركز القومى للبحوث

 

-          Payment Document:  no need for it

- please explain the pilot study in detail 

Comment to the Committee

-          Role/Tasks in The Research/Project: Please put only your role in the study

-          Duration of the Study: Please correct the duration of study because you write 2 month and in Gantt chart 7 month

-          The Protocol Was Reviewed By Scientific Reviewing Committee: he write no although he attach the approval of department

-          Fund Amount: please put the amount of fund

-          How you are going to reduce or mitigate the risks: correct the answer it is not by burning the animal

-           He mention that he will do toxicity test on normal liver cell line but he did not mention any thing about this step and from where he got the cell line

-          A Describe How Pain or Distress Will Be Monitored,  B List Who Will Monitor or Observe Animals and  C Indicate the Schedule of Monitoring:  (A,B,C) They had the same answer that the rat becomes unconscious please  correct them

 لماذا لم يتم تقديم الحصول على موافقة لجنة الاخلاقيات من دكاترة المركز حيث انة مكتوب ان الجزء العملى سوف يتم بالمركز القومى للبحوث

-          What Will Be the Method of Disposal of Dead Animals? Correct the answer

نعم وذلك عن طريق المحرقة بالمركز القومى للبحوث  برجاء تصحيح الاجابة حيث لايوجد محرقة بالمركز القومى للبحوث

 

-          Payment Document:  no need for it

Informed consent form:

N/A

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