Duration of the study:  not 7 days because the duration of the study include all steps of the experiment

The protocol was not reviewed by scientific reviewing committee

Fund amount: is written 10  .

Primary Objective: why were the advantage of the used mentioned in the objective?

Background: please up date to references

Procedure in Details:

1-    In acute toxicity study (LD50): Animals will be observed for 9 weeks this period should be add to duration of the study and in the flow chart

2-In  peptic ulcer model: Group 3 will be received the ethanol dose on 24 h empty stomach, sacrificed after 1 h later and served as the ulcerative rats group.( How?)

Gantt and Flowcharts:

The period of acute toxicity study (LD50)must be add to gantt and flow charts because dose of plant extract will be dependent on results of LD50

List of References: There are 10 references in the list of references but in the procedure  in delails are 5 references

Side effects : no reported side effects ( How?). Although there are not laboratory testes to prove  that no side effect

The researchers did not mention any laboratory test s to measure oxidative stress and inflammatory markers . Are there histopathological samples?

There are no methods to prepare plant extract

All question after the consent form have no answer