The general benefit of the research is use of natural material to control of weight without side effects .

The suspected benefit is target  to humans

The title and the objectives are describe to research topics

Duration of the study: 9 weeks  but it is written in giantt chart 11 week because there are 2 weeks for chemical analyses

Qualifications and experience for Dr. Mona Abdeltawab Esawy   : He has long experience in the field of bioactivity

Background: It is brief and contains 3 references only

Procedure in Details : Please review the animal division section (During the following four weeks, the rats will be given a hypercaloric diet (except the control group) containing 46% commercial food, 46% condensed milk and 8% corn oil (Levin et al. 1986). At the end of four weeks consuming the hypercaloric diet, the animals will be weighed; a sample of blood will be taken and then the animals will be divided into five groups of seven animals each. They will be given the hypercaloric diet and the following treatments for four weeks…..

The method of extracting yeast and  levan is not mentioned  and the source of orlistate was not mentioned

                                      List of References : only  4 references are written

What is the expected severity of pain the animal will suffer in your study : Frequency: No pain is written' although blood samples were taken and the materials used in the experiment were given