National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Design, Synthesis and Characterization of Benzimidazole Derivatives as Angiotensin II AT1-Receptor Antagonists in a Hypertensive Rat Model

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

Test for Toxicity is needed in this study for the determination of the safe and effective doses of the synthesized novel benzimidazole based derivatives, especially for the most potent new compound.

Comment to the Committee

Informed consent form:

N/A

Animal update comments for researcher

Nagwa Ammar

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