National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Comparing the therapeutic potential of free and Nano-formulated lemon grass extract against thioacetamide-induced nephrotoxicity in rats

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

1- إضافة توقيع عميد المعهد علي نموذج 90 

2- إقتراح بتعديل العنوان باللغة العربية إلي دراسة مقارنة للتأثير العلاجي المحتمل لمستخلصي عشبة الليمون الحر و النانوني ضد السمية الكلوية المستحدثة بالثيواسيتامايد في  الجرذان

3- Please modify extract to extracts in the English title.

4- Complete the affiliation of the PI (Institute - Department), as well as the Fund amount.

5- Clarify the name of the PI (Dr. Gada Ibrahim or Dr. Heba Akram).

6- Complete the Precautions needed for the safety of humans and animals when using the toxic substance (Thioacetamide).

7- In the procedure, complete the data related to the tested plant (origin, taxonomical identification, organ used, type of extract, LD50 of the extracts, and toxicological studies or references confirming the safety of using the tested extracts and N-acetylcysteine at a dose of 100 mg/kg).

Comment to the Committee

Informed consent form:

N/A

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