National Research Centre

Medical Research Ethics Committee

MREC Reviewer Comment

Protocol Title

Microbiome signatures in Autism Spectrum Disorder: A Comparative Study with healthy Controls

Completely satisfied and informative data

Needs Explanation

Comments to the applicant

1-suggested to

Change Arabic title to:

بصمات الميكروبيوم في اضطراب طيف التوحد

2-Who will afford for whole exome and Bioinformatics analysis.  Who will afford financially as applicants mentioned it will be self-funded??? e50000. Who will afford financially as applicants mentioned it will be self-funded??? weird amount  50000Egyp. Number of patients are 100 and another 100 control.

3-What is the time period covered by the search:
10 Years?? Explain

4-What about relatives (Relatives from same household of without a history of any disease; Group C) how many and why not included with number of patients(100 patients group A and 100 Group B)).

Comment to the Committee

1-suggested to

Change Arabic title to:

بصمات الميكروبيوم في اضطراب طيف التوحد

2-Who will afford for whole exome and Bioinformatics analysis.  Who will afford financially as applicants mentioned it will be self-funded??? e50000. Who will afford financially as applicants mentioned it will be self-funded??? weird amount  50000Egyp. Number of patients are 100 and another 100 control.

3-What is the time period covered by the search:
10 Years?? Explain

4-What about relatives (Relatives from same household of without a history of any disease; Group C) how many and why not included with number of patients(100 patients group A and 100 Group B)).

Informed consent form:

Needs Modification

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