Clarification is required regarding the primary objective. Are you conducting an assessment of the ulcer-related pain? or is it the influence of laser and HA on the management of RAS-related pain? This way there is no necessity to evaluate the efficacy of both interventions if the primary objective is to evaluate the pain associated with ulcers.

The duration of the study needs to be adjusted. One month is not enough to gather 54 patients presenting the study's inclusion and exclusion criteria, never the less treating those patients with the proposed management strategy. Kindly correct the study duration. 

Please provide clarification on the calculation of the laser dosage and include a supporting reference.

In the methodology section, please mention how many laser sessions. Kindly add all the information related to the parameters of laser application.

Also, what is the duration of the treatment with HA?

Sample size calculation relies on a singular study assessing the effect of HA alone, with no references supporting the use of laser intervention in recurrent aphthous stomatitis. Consequently, the calculation of sample size requires re-evaluation with additional supporting references.

The informed consent needs thorough revision. Kindly remove any unnecessary information. Also, try to simplify the information provided to the patients. The section regarding pregnancy needs to be deleted since it is not relevant to the addressed age group.