Kindly provide additional information regarding the composition / constituents of the suggested new irrigation solution.
Kindly indicate the location where the extracted teeth will be obtained and whether those clinics offer broad informed consent. If not kindly provide an Informed consent document.
Please provide further details regarding the source of the E. faecalis strain and the place where will the antibacterial assessment be conducted ?

For the cytotoxicity testing, kindly specify the type of cells you will be working on, the site of acquisition and the place of testing.

Both the Flow chart and the Gant chart are missing. Kindly submit both.